Find the right treatment for you for your osteoarthritis knee pain.

If you are diagnosed with osteoarthritis of the knee, your doctor may recommend one or more of the following treatment options to reduce your symptoms:

  • Lifestyle changes — including moderate exercise, weight control and reducing stress on your joints
  • Oral pain relievers — such as acetaminophen (e.g. Tylenol®), NSAIDs (e.g. Aleve® and Motrin®) and COX-2 inhibitors (e.g. Celebrex®)
  • Topical pain-relieving creams — to apply to your skin
  • Physical and occupational therapy — to strengthen muscles and improve mobility
  • Steroid injections — to temporarily relieve pain and reduce any swelling 
  • Viscosupplement injections (also called hyaluronic acid injections) — a knee injection, such as Synvisc-One® (hylan G-F 20), that replaces damaged joint fluid with a substance similar to healthy joint fluid in order to reduce pain
  • Surgery — often recommended when knee pain is severe and other treatments have not provided relief
NEXT: What Is Synvisc-One?

PLEASE NOTE: Tylenol is a registered trademark of The Tylenol Company. Motrin is a registered trademark of Johnson & Johnson. Celebrex is a registered trademark of G.D. Searle, LLC.

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A doctor's perspective

"Many of my patients are concerned about the risks of taking medications all the time. Synvisc-One may give them the ability to lessen their need for pain pills or maybe completely avoid them."

 — Dr. DiNubile, orthopaedic surgeon and sports medicine specialist

Learn more about Synvisc-One

Indication

Synvisc-One® (hylan G-F 20) and SYNVISC® (hylan G-F 20) are indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

Important Safety Information

Before trying Synvisc-One or SYNVISC, tell your doctor if you are allergic to products from birds — such as feathers, eggs or poultry — or if your leg is swollen or infected. Synvisc-One and SYNVISC are only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One and SYNVISC have not been tested to show pain relief in joints other than the knee. Talk to your doctor before resuming strenuous weight-bearing activities after treatment. Synvisc-One and SYNVISC have not been tested in children, pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child. The side effects most commonly seen when Synvisc-One or SYNVISC is injected into the knee were pain, swelling and/or fluid buildup in or around the knee. Cases where the swelling is extensive or painful should be discussed with your doctor. Allergic reactions such as rash and hives have been reported rarely.

View the Complete Prescribing Information for Synvisc-One (PDF)
View the Complete Prescribing Information for SYNVISC (PDF)