For U.S. Residents Only Synvisc-One

Find tips, advice and inspirationin our Knee Exercise Center.

3-Step Knee Exercise Program

Want to strengthen your muscles, improve flexibility and help reduce knee pain? Try these exercises designed specifically for patients with osteoarthritis.

Watch Videos
You should consult your doctor before starting any new health or exercise regimen.
Exercise That’s Really Fun — and Really Good for Knee Osteoarthritis

Three activities proven to help your knees and fun enough to keep you coming back for more.

Weight-Loss Tips that Work

Four helpful tips that could put you on the path to maintaining a healthy weight.

A Patient’s Guide to Understanding NSAIDs

Read up on the pros and cons of the three types of oral pain relievers known as NSAIDs.

6 Ways to Make Bike Riding Fun Again

Check out six simple ways to help you get on the road to a pain-free ride.

Pain Relievers: Handle with Care

They're a convenient way to manage some pain, but do you know the risks?

4 Foods that May Help Fight Knee Osteoarthritis

See how the right diet could make all the difference in fighting knee osteoarthritis.

Working Out Through Osteoarthritis Pain

Two experts discuss how pain impact exercise — and what you can do about it.

Brace Yourself! Handy Helpers for Your Knees

Research shows a little help can go a long way in the stability of your knees.

10 Tips to Help You Dig in to Painless Gardening

Rediscover your favorite activity with ten tips that can help knee pain from sprouting.

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Indication

Synvisc-One® (hylan G-F 20) is indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

Important Safety Information for Synvisc-One

Before trying Synvisc-One, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. Should not be used in patients with an infected knee joint, skin disease or infection around the area where the injection will be given, or circulatory problems in the legs.

Synvisc-One is only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One has not been tested to show pain relief in joints other than the knee. Tell your doctor if you are allergic to products from birds – such as feathers, eggs or poultry – or if your leg is swollen or infected.

Synvisc-One has not been tested in children (≤21years old), pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child.

Talk to your doctor before resuming strenuous weight-bearing activities after treatment.

The side effects sometimes seen after Synvisc-One include (<2% each): pain, swelling, heat, redness, and/or fluid build-up in or around the knee. Tell your doctor if you experience any side effects after treatment with Synvisc-One.

View the Complete Prescribing Information for Synvisc-One (PDF)

Indication

SYNVISC® (hylan G-F 20) is used to relieve knee pain due to osteoarthritis (OA). It is for patients who do not get enough relief from simple painkillers such as acetaminophen, or from exercise and physical therapy.

Important Safety Information for SYNVISC

Before trying SYNVISC, tell your doctor if you have had an allergic reaction, such as swelling of the face, tongue or throat, respiratory difficulty, rash, itching or hives to SYNVISC or any hyaluronan-based products. Should not be used in patients with an infected knee joint, skin disease or infection around the area where the injection will be given, or circulatory problems in the legs.

SYNVISC is only for injection into the knee, performed by a doctor or other qualified health care professional. SYNVISC has not been tested to show pain relief in joints other than the knee. Tell your doctor if you are allergic to products from birds - such as feathers, eggs or poultry - or if your leg is swollen or infected.

SYNVISC has not been tested in children (≤21years old), pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child. Talk to your doctor before resuming strenuous weight-bearing activities after treatment.

The side effects sometimes seen after SYNVISC include pain, swelling, heat, redness, and/or fluid buildup in or around the knee. These reactions were generally mild and did not last long, but in rare occasions these side effects were more severe. The most commonly occurring adverse events outside of the injected knee were rash, fever, nausea, and headache.

View the Complete Prescribing Information for SYNVISC (PDF)

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Important Safety Information: SYNVISC and Synvisc-One are contraindicated in patients with known hypersensitivity to hyaluronan products or patients with infections in or around the target knee.