Synvisc-One® (hylan G-F 20) is a viscosupplement injection. Made from a natural substance that lubricates and cushions your joint, it can provide up to six months of osteoarthritis knee pain relief with just one injection.
What is Synvisc-One?
In knees with osteoarthritis, the joint fluid (called synovial fluid) can break down and not provide the cushioning your knee needs.
Synvisc-One supplements your knee joint fluid to relieve the pain and improve the knee joint’s natural shock absorbing abilities.
A. Cartilage wears away B. Bone spurs may develop C. Joint fluid breaks down
D. Synvisc-One replaces joint fluid
Who is a candidate for Synvisc-One
Patients with knee osteoarthritis who have tried diet, exercise and over-the-counter pain medication but still have pain, should talk to their doctor to see if Synvisc-One is right for them.
How Synvisc-One is administered
Synvisc-One is a single injection. It’s a simple, in-office procedure that only takes a few minutes.
What you can expect following a Synvisc-One knee injection
Synvisc-One can provide up to six months of osteoarthritis knee pain relief. Everyone responds differently, but in a medical study* patients experienced relief starting one month after the injection.
After the injection, you can resume normal day-to-day activities, but you should avoid any strenuous activities for about 48 hours.
*Chevalier X, Jerosch J, Goupille P, et al. Single, intra-articular treatment with 6 ml hylan G-F 20 in patients symptomatic primary osteoarthritis of the knee; a randomised, multicentre, double-blind, placebo controlled trial. Ann Rheum Dis. 2010;69(1):113-119. doi:10.1136/ard.2008.094623.
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